Inter Milan staged a late smash-and-grab raid as goals by Mauro Icardi and Matias Vecino secured a 2-1 home win over Tottenham Hotspur in their Champions League Group B opener on Tuesday.
Barcelona's lead at the top of La Liga was cut to two points on Saturday as they squandered a two-goal advantage to draw 2-2 at Sevilla while Real Madrid powered their way to a 3-0 home win over Eibar.
Lionel Messi, Luis Suarez and Neymar combined to devastating effect as Barcelona swatted Celtic aside 7-0 at the Nou Camp to lay down a marker in Champions League Group C on Tuesday.
A round-up of Wednesday's league stage matches in the UEFA Champions League.
Barcelona's Luis Suarez netted twice for a 2-1 win over 10-man Atletico Madrid in their Champions League quarter-final, first leg on Tuesday after the visitors' Fernando Torres opened the scoring and was later sent off.
News of all that's transpired on and off the football field
Images from the Champions League round of 16 second leg matches played on Tuesday
Cristiano Ronaldo set a record for goals scored in the group stage of the Champions League of 11 when he netted four against Malmo in Group A on Tuesday.
Robert Lewandowski scored a brilliant free kick to give Bayern Munich a 1-0 win over Atletico Madrid in their last Champions League Group D outing on Tuesday, ending the 100 percent record of their opponents. The Poland international curled the ball over the wall and into the corner of the net in the 28th minute but the goal had no impact on the final standings with Atletico guaranteed top spot and Bayern in second place.
Atletico Madrid got their La Liga campaign up and running in less than convincing fashion when Antoine Griezmann's deflected free kick secured an edgy 1-0 win at home to promoted Las Palmas on Saturday.
Barcelona must to wait to confirm a place in the Champions League last 16 after dropping points for the first time in Group D in an absorbing 0-0 draw at Olympiakos Piraeus on Tuesday.
News of all that's transpired on and off the football field
Photos from the Champions League matches played across Europe on Tuesday
Coach Pep Guardiola was left thrilled after ManchesterCity revived their Champions League bid by beating his old club Barcelona 3-1 in a gloriously open Group C encounter at the Etihad Stadium on Tuesday.
Photos from the Champions League matches played across Europe on Tuesday
